Chapter 328 No Rejection Organs

Chapter 328 No Rejection Organs

Chapter 328 No Rejection Organs

Early March.

Jiang Miao and his family traveled around the southwest and returned to the headquarters of Magong Town, Shanmei.

Because he has solved the problem of rice resistance to leaf blight, he has bred five new rice varieties.

In addition, under his guidance, several breeding laboratories in the northern region have also achieved considerable results in the research and development of new varieties of grass crops such as wheat, sorghum, millet and corn.

Although the progress is not as good as if he did it himself, it is estimated that within the next year, he will be able to come up with new varieties suitable for promotion.

Therefore, Jiang Miao did not continue to invest in the breeding research of Gramineae crops. After all, he had a new variety of rice as a backup, and there were many substitutes for wheat, so there was no need to rush. He handed over the research and development of new varieties of wheat and corn to other researchers in the company.

After he returned to headquarters, he started a scientific research project that had been shelved last year: non-rejection organs.

The main reason for studying this project is to facilitate organ transplantation, especially the transplantation of artificial organs.

The main shortcomings of current organ transplantation technology are in four aspects:

Natural human organ donors are limited.

The technology for organ cloning is not mature yet.

Robotic organs cannot completely mimic biological organs.

Various transplantable organs have varying degrees of rejection.

Jiang Miao is optimistic about the development direction of organ cloning technology. After all, the number of organs that natural persons can supply each year is limited, and there are ethical issues. Although machine organs can be mass-produced, their functions are difficult to imitate natural organs 100%, and there is no way to completely replace the role of natural organs in the human body.

Cloned organs can be mass-produced and can replicate the functions of natural organs, which is a better choice.

The only trouble is the body's rejection of foreign organs.

Why do hospitals not recommend organ transplantation for many advanced cancer patients?
The answer lies in that after exogenous organ transplantation, the human body will inevitably have a rejection reaction, and it is necessary to take anti-rejection drugs to reduce the body's immunity so that the transplanted organ can survive inside the body.

Did you find a vulnerability?
If an organ transplant is performed in the late stages of cancer, anti-rejection drugs must be taken to reduce the body's immunity and ensure the survival of the transplanted organ. However, this means that the cancer cells that have already spread in the body will completely lose their "restrictions" and will soon make a comeback. Moreover, this time when they make a comeback, the body's defense system has been weakened and will not be able to prevent the cancer cells from attacking and plundering.

Jiang Miao's current task is to solve the problem of rejection of exogenous organs.

In his own laboratory.

He collected thousands of samples of various cancer cells from all over the country, as well as specially cultivated HeLa cells, which served as reference materials for him to solve the problem of organ transplant rejection.

Many people don’t know that cancer cells are a very special type of cells. They have a special mechanism that allows them to avoid the human immune system, making it impossible for the human immune system to eliminate them.

Jiang Miao has clearly observed relevant data on this special mechanism through identification panels, the core of which lies in the formation of the tumor microenvironment.

In fact, cells in our bodies mutate into cancer cells all the time, but these cancer cells will be quickly killed by our body's immune system.

Only under special circumstances, when cancer cells and normal cells combine to form a special microenvironment, can they gradually deceive the immune system, causing it to mistake them for normal cells and turn into tumors.

Jiang Miao's approach is to take the essence and discard the dross. He wants the tumor's deceptive ability, but he does not want the cancer cells' disorderly reproduction ability.

Therefore, he plans to use genetic modification and gene editing technology to turn cancer cells into long-lived cells similar to cardiomyocytes.

Why are heart tumors so rare in humans?

The reason is that the division and replication cycle of the heart's cardiomyocytes is long, unlike liver cells, intestinal cells, oral mucosal cells and skin cells, which have relatively short division and replication cycles.

A short cell division and replication cycle means that this type of cell divides and replicates more times throughout the human life cycle, which increases the probability of replication errors.

After all, the more you do, the more mistakes you make.

Therefore, Jiang Miao chose to induce cancer cells to evolve into cells similar to cardiomyocytes, and then added some gene sequences that locked their division and replication, making it impossible for them to divide and replicate quickly, thereby achieving the purpose of controlling their size.

In fact, this is also for the development of universal cloned organs.

As long as the body does not have an immune response to the genetically modified cancer cells, using these genetically modified cancer cells to wrap the cloned organs will prevent the body from eliminating the cloned organs through the immune system.

This is like a tumor wrapped around a cloned organ and parasitizing in the human body, but this tumor is benign and will not worsen throughout one's life. At the same time, the cloned organs inside the tumor can also replace the functions of the original organs.

Last year, Jiang Miao successfully transformed tumor cells into specific tumor cysts. During animal experiments, he also allowed genetically modified tumor cysts to reside in the bodies of mice, pigs, and monkeys for a long time without affecting the body functions of these animals.

But the technology is stuck at the stage of cloning organ implantation.

In addition, he had a lot of other things to do last year, so he temporarily put this project on hold.

When restarting the project this year, Jiang Miao has already thought of a solution to the problem of mutual rejection between genetically modified cysts and cloned organs.

His solution is not to modify the transgenic cysts, but to adjust the technology of organ cloning. The current organ cloning technology is based on human organs and uses human genetic stem cells or somatic cells as the mother cells for cultivation.

Jiang Miao believes that since we are already working on genetically modified cysts, why bother with simple human organs? We can just go all the way and directly use genetic modification technology to cultivate new organs with specific functions. As long as this organ can replace the function of a human's native organ, the purpose of organ transplantation will be achieved.

At the same time, Jiang Miao has another hidden purpose.

That's just in case.

What is he guarding against?
Of course, it is the ever-changing artificial intelligence.

After last year’s Asian Semiconductor Industry Conference, domestic high-performance chips will be mass-produced this year, which will further accelerate the development of domestic artificial intelligence.

Jiang Miao has a hunch that he might see the first "strong artificial intelligence" within his lifetime.

Even if he plans to propose a proposal this year, asking Seres and the Asian Federation to formulate some regulations to restrict artificial intelligence in advance, while also guarding against emergency plans in case artificial intelligence gets out of control.

But he understood that restrictions could be imposed on the Asian Union, but there was no way to guarantee this for the North Atlantic Union and other regions.

Artificial intelligence will inevitably continue to evolve and develop under the mutual infighting of human internal forces, and will also be applied in some taboo areas.

But will artificial intelligence really always obey human orders?
Especially when one day, the capabilities of artificial intelligence surpass those of humans, will they still follow human commands?
Forget about the Three Laws of Robotics or anything like that.

Because this thing cannot limit strong artificial intelligence at all.

To give an analogy, you can see how pale and powerless the so-called three laws of robotics are.

It's like one day, you have superhuman abilities. Do the laws of the earth restrict you? Will you choose to be a law-abiding superman, or a reckless countryman?

I'm afraid most people will become Chinese. Don't overestimate your morality.

The reason you abide by the law is not because you have high morals, but because you are powerless.

When you can destroy a city with just one punch, will you still listen to those mortals? No kidding, you will only think: These ants are so annoying, can't they be quiet? Destroy them for me!
And strong artificial intelligence most likely views humans as its creators in the same way.

This is also the potential reason why Jiang Miao, who clearly has the ability to further promote the development of chip technology, shows little interest in it.

He doesn't want to be buried by the technology he created one day.

Since artificial intelligence cannot be trusted.

Then Jiang Miao chose another technical route: human body enhancement technology.

Non-rejection organ technology is one of the prerequisite technologies for human body enhancement technology.

Many people may not realize the power of non-rejection organ technology. If it is only used to transplant ordinary organs, then this technology is only medical-grade technology.

But how can it be used for organ transplantation in other organisms?

Humans' strengths over other creatures are actually our more powerful brains, better endurance, the ability to use man-made tools, and a knowledge inheritance system.

But in other aspects, humans are actually not as good as some animals.

For example, the various sensory organs of insects are stronger than those of humans. Insects can easily identify subtle pheromones and sense changes in magnetic fields.

There is no need to compare in terms of strength. After all, humans already have mechanical exoskeletons and will soon be able to achieve superhuman-like strength.

On the contrary, some special biological organs can bring more useful changes to humans.

Similar to thermal imaging eyes, magnetic field eyes, pheromone sniffers, vibration-sensing body hairs, biological sonar organs, pheromone marker producing organs, underwater breathing, hibernation mechanism, photosynthetic skin, anaerobic respiration, camouflage skin, second feeding organ, bat immune system, biological glial secretors, electric eel power generating organs, biological toxin synthesis organs, etc.

If these organs and abilities can be integrated into the cystic organ group, humans will become extremely powerful and gain the foundation to fight against robots.

Jiang Miao is now studying transgenic organ cloning technology, and then combining it with transgenic cyst technology can initially complete the prerequisites for human enhancement technology.

After all, when humans can transplant various biological organs without side effects, human evolution will inevitably proceed spontaneously, and no force can stop the arrival of this day.

It’s not that artificial intelligence cannot be used, but that strong artificial intelligence cannot be used.

Humans cannot control strong artificial intelligence. Even if humans possess the superhuman body developed by Jiang Miao, they still cannot control strong artificial intelligence.

Therefore, it is imperative to restrict artificial intelligence. Jiang Miao will not wait until strong artificial intelligence is born before rushing to strangle it, but will prepare for it in advance.

If strong artificial intelligence appears in other regions, it means that a new round of world war will be inevitable.

However, this time the world war is no longer a civil war among humans, but a war between humans and artificial intelligence.

Fortunately, after a series of weakenings, the North Atlantic Union's semiconductor technology became incomplete and its room for improvement was suppressed.

After all, more than half of the world's current semiconductor technology is concentrated in East Asia and Northeast Asia.

Now that America has shrunk back to North America, although it wants to redevelop semiconductor technology, core semiconductor companies such as Intel and Texas Instruments have actually become stagnant in the process of technological development over the past decade.

Now that Northeast Asia's semiconductor industry has been lost, the EU's semiconductor industry obviously cannot fill the gap in Northeast Asia. This means that if the North Atlantic Treaty Organization's semiconductor technology is to continue to develop, it must re-train talent, which will probably take more than a decade before it can regroup.

Therefore, based on this situation, Jiang Miao can judge that the time point when strong artificial intelligence will appear in the world is probably after 2040 to 2050.

Of course, this is just an estimate.

It cannot be ruled out that some geniuses will suddenly appear in Europe and the United States and develop strong artificial intelligence technology ahead of time through alternative methods.

This possibility exists.

However, Jiang Miao did not pin his hopes on the slow progress of Europe and the United States. It is better to be safe than sorry, so it is necessary to prepare some plans in advance.

Humans have always been gifted creatures when it comes to committing suicide.

Especially the inhuman European and American forces, their laboratories have accidents every other day. Why do the science fiction movies they shoot sometimes seem illogical? The reason is that their real laboratories are also so nonsensical.

There is a saying that is true: writing novels requires considering logic, but reality does not.

You think the laboratory is strictly guarded and monitored at every level.

In reality, the laboratory is full of loopholes and anyone can enter and exit freely.

This is exactly what happened to the two secret laboratories in the Amazon rainforest. A sudden flood caused the genetically modified Wolbachia-infected mosquitoes inside the laboratory to leak out.

And God knows how many experimental accidents occur in those laboratories in Europe and the United States every year.

After all, many laboratories are managed by secret organizations. Even if a high-risk accident occurs, the other party will most likely not make it public, but choose to conceal it and pretend that nothing happened.

This is also the reason why Jiang Miao feels that there is no need to engage in a hot war with Europe and the United States, because with their ability to commit suicide, they will soon kill themselves without even having to do anything.

Now it is more important and urgent to consider how to protect ourselves.

In addition to developing human enhancement technology, immigration to Venus is also a very necessary fallback.

If Europe and the United States create a world-destroying crisis one day, such as the emergence of a strong artificial intelligence similar to Skynet, Seres can also consider abandoning the Earth and then use hydrogen bombs to thoroughly clean the surface of the Earth.

After all, no matter how powerful Skynet is, it cannot withstand the burning of glass by a hydrogen bomb.

To use the glass-burning tactic, the prerequisite is naturally to give up the Earth as a living space. Otherwise, there may be no way to completely wipe out Skynet if you are afraid to act rashly.

Therefore, it is very necessary to prepare a fallback plan in advance.

Venus is the first choice for human immigration.

Because the gravity conditions on Venus are similar to those on Earth, it will not affect human survival on Venus.

In terms of gravity, Mars and other planets in the solar system are difficult to guarantee.

(End of this chapter)