Chapter 332 Subject

Chapter 332 Subject

Chapter 332 Subject

In 2029, the Northern Hemisphere entered a hot summer.

In addition to handling company affairs on a regular basis, Jiang Miao has recently devoted all his energy to the research and development of non-rejection organs.

At this time, he was in his own laboratory.

If a stranger enters, he might be frightened by the scene.

In each cloning culture chamber, there were either lumps of flesh growing or various human organs growing.

Especially in the eyeball cultivation cabin, through the glass of the observation window, you can see eyeballs. The pupils in the eyeballs are emotionless and just staring blankly.

It gives people goose bumps.

However, the researchers working in this laboratory were not surprised by this and were busy with their own work.

"Boss, the 12th batch of genetically modified eyeballs has been cultivated."

Jiang Miao looked at the eye tissue slices under the microscope and ordered without turning his head: "Ah Hai, take your men to implant these eyeballs into the genetically modified capsules."

"No problem." Ah Hai pushed up his glasses and replied.

After a while, Jiang Miao sat back in his seat and let out a long breath: "Huh..."

He picked up the laboratory tablet beside him and called up some test reports and analysis reports from today. After reading them for more than ten minutes, he narrowed his eyes slightly and fell into deep thought again.

The genetically modified tumor capsules specifically for the eyes were successfully developed in November last year and have undergone five rounds of animal experiments, basically reaching the stage where human experiments can be carried out.

However, since the artificial genetically modified eyeballs were not successfully developed, human experiments were delayed again and again.

In the past few days, the artificial genetically modified eyeballs have finally been adapted to the cyst, and no obvious rejection reactions occurred during animal experiments.

Just as Jiang Miao was thinking about the next arrangement, a light and rhythmic sound of footsteps came from outside the corridor.

bang bang bang...

There was a knock on the door followed by a muffled call.

"Boss, the human experiment project you applied for has been approved today. Here are the relevant license documents." Scientific research secretary Shan Yijun came to his side to report on his work.

Jiang Miao did not feel surprised at all. After all, with his current status and position, coupled with his well-known scientific research capabilities, there would be basically no obstacles in applying for this kind of human experiment project.

"Mr. Yi, how is the recruitment of research subjects going?"

Shan Yijun was well prepared. After all, this was his job. He immediately replied, "Boss, Hailufeng Hospital has already recruited 50 relevant subjects. They are all blind patients with eye diseases."

Jiang Miao shook his head: "Not enough, recruit another 100 people as subjects for the second phase of clinical trials."

"No problem, I'll ask someone to expand the recruitment later." Shan Yijun didn't think this was difficult.

On the one hand, Jiang Miao’s reputation can give many patients confidence.

On the other hand, the subsidies for Hailufeng Hospital are very generous.

You should know that most blind patients have basically lost their ability to work and a large part of their ability to take care of themselves. If the family is wealthy, it is not so bad. But if it is an ordinary family, having a blind patient is a huge burden and may even cause the family to quickly fall into poverty.

Therefore, during the first round of recruitment, thousands of patients from ordinary families signed up to participate, but in the end only fifty patients passed the approval.

Now we just need to send out an announcement and we can quickly recruit another hundred people.

Of course, one hundred people are only enough for the second phase of clinical trials.

When it comes to the Phase III clinical trial stage, it is estimated that another 500 to 1,000 patients will be recruited for testing.

However, the subsidies for each phase of clinical trials are different.

The first phase has the best benefits but also the greatest risks.

The second phase benefits are moderate, and the risks are also moderate.

The benefits of the third phase are average and the risks are minimal.

After sending Shan Yijun away, Jiang Miao left the laboratory to take a breath, drank a bottle of special functional drink, and then returned to the laboratory.

At this time, Ahai and others had implanted the 12th batch of artificial eyeballs into the capsule.

These genetically modified capsules, specially customized for human eyes, look like a flesh-colored leather case, half-wrapping the artificial eyeball.

By simulating neural electrical signal stimulation, it is possible to analyze whether the functions of these eyeballs are normal.

Seeing Jiang Miao coming over, Ah Hai stood up and reported the situation: "Boss, the eyeball function is normal, no abnormality was found."

Jiang Miao took a look at the eyeballs and casually ordered, "Continue testing to see if there is any rejection reaction."

"Ok."

In fact, Jiang Miao has analyzed the compatibility between these eyeballs and cysts through the identification panel. In this way, he also adjusted the genes of the eyeballs little by little, so that the compatibility between them and the genetically modified cysts reached more than 99.9%.

The genetically modified capsules are also specially customized.

For example, these eye cysts not only make the human immune system "blind" to them, but also carry special neuronal structures that allow the eyeball and brain nervous system to connect quickly and accurately.

If the latter function is not available, then even if the human immune system does not attack the transgenic capsule and transgenic eyeball, the function of the eyeball cannot be exerted, which is equivalent to the implant being in vain.

These are also the two core functions of the cysts. Only with these two functions can the genetically modified cysts and genetically modified organs be safely implanted into the human body and allow the organs to perform their due functions.

In the following week, the 12th batch of transgenic artificial eyeballs not only completed non-rejection adaptation in the capsule, but also successfully enabled these eyeballs to function as they should through transgenic capsules customized for monkeys and domestic pigs.

No anti-rejection drugs were used on the experimental animals, and no obvious rejection symptoms were observed.

The time comes on June 5th.

Jiang Miao, along with several researchers and an ophthalmic surgery team arranged by Hailufeng Hospital, started the first transplant operation at Hailufeng Hospital in Magong Town in the urban area.

The subject's family members were also present.

Seeing the subject's bed being pushed into the operating room by the nurse, the family members suddenly became nervous.

Jiang Miao did not go in, but several researchers went into the operating room. Because these researchers have performed related transplant operations on animals, with their cooperation with the professional ophthalmic surgery team, the safety will be higher.

Of course, considering that this was the first transplant experiment, just in case, the subject only underwent a transplant on his left eye.

The right eye depends on the transplant situation of the left eye. If the vision function of the left eye returns to normal after the transplant and there is no obvious rejection reaction, the hospital will arrange a transplant operation for the right eye three months later.

Jiang Miao sat in the office on one side of the operating room.

He casually flipped through the subject's medical records and family profile.

This man is called Wang Bingdong, from Meicheng, Lingnan. He is 39 years old this year. He became blind due to delayed treatment of corneal disease.

If the eye disease is caused by high blood pressure and diabetes, a simple eye transplant will not be able to cure it. This is because if high blood pressure and diabetes are not controlled, even if an eye transplant is performed, the patient will soon become blind again.

Two hours later.

Ah Hai pushed the door open and walked in.

"Boss, I'm glad you did what you asked. The operation was a great success."

"Have the family been notified?"

"The attending physician has already informed me."

"That's good. I'll go over and take a look after he's sent to the ICU." Jiang Miao didn't leave right away, mainly because he didn't want to meet the family members. It wasn't that he was being hypocritical, but he had arranged related human experiments before, and many family members were concerned and confused, and didn't understand the relevant medical terms, and even showed only a vague understanding of the vulgar descriptions.

When faced with such family members, the more he explained, the more worried they became.

That's why he didn't meet the subjects' families.

This is the attending physician.

"Please rest assured, family members, the operation was very successful. The patient needs to be in the intensive care unit for the next few days. You don't need to worry about anything else."

The subject's wife was so nervous that her hands were shaking: "Doctor, when can we go visit?"

The doctor gave a clear time according to the arrangement: "Wait three days!"

"Three days later? Okay, thank you, doctor." The subject's brother was relatively calm: "Three days later, what do we need to prepare?"

"No, the patient is a research subject. All expenses are covered by our hospital. You just need to get some rest. You don't need to worry about anything else."

"Thank you, doctor..." The subject's old father took out a red envelope from his pocket and handed it to the attending physician.

The attending physician shook his head and handed the red envelope back: "No need to do that, our hospital does not accept red envelopes, and you are research subjects, even if you want to give a red envelope, our hospital will give it to you."

"Dad, please don't make things difficult for the doctor."

"I'm very sorry, doctor. My dad has old-fashioned ideas. Please forgive me."

The attending physician smiled and said, "It's okay. I have something else to do. I'll excuse you now."

"Doctor, please be busy first. We won't bother you anymore."

After a while, the door of the operating room opened.

The subject, who was still under anesthesia, was pushed out on the bed and transferred to a special intensive care unit.

Jiang Miao also secretly came to the intensive care unit through another passage.

He and Ah Hai stood beside the bed and looked at the data from the monitoring equipment, especially the advanced version of the human vital signs nano-monitor, which can monitor the patient's various physical indicators anytime and anywhere.

Of course, Jiang Miao was just pretending, because he mainly relied on the identification panel to observe the patient's condition.

Ah Hai said softly: "The situation is still relatively ideal. There are no obvious abnormal data in various indicators."

Jiang Miao nodded silently.

Through the identification panel, he knew the subject's condition better than anyone else, especially the neural connection between the eyes and the brain.

It will take about a week for the subject's visual nervous system to merge with the neural structure of the capsule, and then the function of the genetically modified eyeball can be activated by continuous stimulation with simulated neural electrical signals.

Over the next week or so.

Jiang Miao was always paying attention to the condition of the subject and visited him twice during this period.

Until the sixth night.

By identifying the data on the panel, he discovered that the subject's optic nerve and the neural structure of the capsule had been initially fused together.

The gauze on the subject's eyes was also removed.

The attending physician began trying to stimulate his optic nerve this evening while guiding the patient through verbal guidance.

"Mr. Wang, imagine that your eyes can see things..."

The subject Wang Bingdong's left eye rolled around, and then he felt a little dazzling and numb in his eye.

This is actually the nanoneedles that simulate neural electrical signals continuously stimulating his ocular nervous system.

After a while, tears started to flow from his left eye.

"Doctor, my brother's eyes are tearing up!"

"It's okay, this is normal." The doctor's face lit up with joy. The tears in Wang Bingdong's left eye proved that he felt the light in the environment and his retina was stimulated by the light, which caused him to start shedding tears.

Before I knew it, more than an hour had passed.

"Doctor, I saw something!" Wang Bingdong's voice trembled slightly.

The attending physician did not press on, but chose to stop: "Okay, that's all for tonight. Now lower the brightness in the ward. Your eyes are recovering little by little. It may take more than ten days to fully activate the function of your eyes. Don't worry. Draw the curtains in the ward tomorrow so that you are not exposed to strong light all at once."

"Okay, doctor." After there was hope for his eyes to recover, Wang Bingdong's mood suddenly improved and he behaved very cooperatively.

However, the attending physician did not completely believe the subject. After leaving the ward, he immediately instructed the head nurse to pay special attention to this ward.

Jiang Miao also observed the physical condition of the subject through the one-way glass observation window in the next room. After finding that there was nothing abnormal, he left the hospital with peace of mind.

arrive home.

Just washed my hands and sat down.

Shuya brought her daughter down from the second floor.

"father!"

"Douzi! Come here, let daddy hold you."

"No! Daddy's beard pricks me." Douzi hugged her mother's calf in a dirty way and just didn't want to be hugged by him.

Jiang Miao pinched her little face helplessly: "My Douzi doesn't love Daddy anymore, so Daddy won't take you out to play in the future."

"Mom and grandma will take care of me." Douzi's little face looked like a little bun.

Shuya picked up her daughter and said, "Why have you been so naughty these days? You are becoming less and less cute. If you don't listen, Mom will be unhappy."

Douzi said aggrievedly: "Oh... I just don't like dad's beard pricking me, it's not disobedient, mom, don't be angry..."

"Okay, Dad will go shave later."

One of the housekeepers came over with a small box of electric razors: "Sir, a razor."

"Thank you, Mrs. Li."

Jiang Miao picked out a more user-friendly electric shaver, pressed the switch, and started shaving around his mouth.

While combing her daughter's hair, Shuya asked, "Did you go to see the subject again?"

"Ah."

"How's it going?"

"The transplant was quite successful. I can already see something. There is no obvious rejection reaction."

"It seems your idea was successful."

"It's just one of the projects. There are so many organs in the human body. It will take five or six years to complete the research and development of a full set of human organs."

Mrs. Li at the side was also listening very carefully. Her husband was diagnosed with kidney failure last year and can only maintain a normal life by implanting a portable nanodialyzer.

Therefore, she very much hopes that the artificial kidney can be successfully developed, so that she doesn't have to worry too much.

But she was already relatively lucky. After all, she could come to Jiang Miao's house to work, and the various benefits were definitely enough to cover all the expenses for her and her husband.

(End of this chapter)